Author

Paolo Chetta

Boehringer Ingelheim (Germany)ORCID 0009-0002-2408-0239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Alan A. MelcheriD· 1 shared Alexandra Hörmann· 1 shared Alexandra PopaiD· 1 shared Anna KöferleiD· 1 shared Anne B. VogtiD· 1 shared Anton PatrikeeviD· 1 shared Antonio RullaniD· 1 shared Charleen Chan Wah HakiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alan A. MelcherORCID

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2 papers

Recent·Most cited

Preclinical efficacy of a systemically-administered, second-generation STING agonist that promotes antitumour immunity in combination with radiotherapy

Malin Pedersen, Lisa C. Hubbard, Shane Foo, Anton Patrikeev, Antonio Rullan, Holly Baldock, Christian Mandl, Paolo Chetta, Jehanne Hassan, Isaac Dean, Naomi Guppy, Philippe Slos, Charleen Chan Wah Hak, Elizabeth S. Appleton, Emmanuel Christian Patin, , Kevin J Harrington

This study evaluates a second-generation STING agonist, BI-1703880, showing that combining it with radiotherapy enhances antitumour immunity and immune memory.

bioRxiv · Mar 25, 2026 · PreprintCancer Biology

Precision RNAi using synthetic shRNAmir target sites

Thomas Hoffmann, Alexandra Hörmann, Maja Corcokovic, Jakub Zmajkovic, Matthias Hinterndorfer, Jasko Salkanovic, Fiona Spreitzer, Anna Köferle, Katrin Gitschtaler, Alexandra Popa, Sarah Oberndorfer, Florian Andersch, Markus Schaefer, Michaela Fellner, Nicole Budano, , Ralph A. Neumüller

This paper introduces ARTi, a method using synthetic shRNAs to achieve precise and controllable RNAi for gene suppression.

eLife · Aug 8, 2023Peer-reviewedGenetics