Florian Andersch

The paper uses CRISPR screens to identify regulators of immunosuppressive surface molecules in cancer cells, finding DNAJC13 as a key regulator that enhances T-cell sensitivity and tumor survival.

The paper identifies AKIRIN2 as a multivalent adaptor protein that coordinates proteasome nuclear import through a stepwise assembly of importin clusters.

This paper introduces ARTi, a method using synthetic shRNAs to achieve precise and controllable RNAi for gene suppression.