Author

Sara N. Filippelli

Purdue University West LafayetteORCID 0009-0002-2449-4247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Amber L. MosleyiD· 1 shared Brittany L. Allen-PeterseniD· 1 shared Brittany N. HeiliD· 1 shared Claire M. PfefferiD· 1 shared Emma H. DoudiD· 1 shared Garima BaraliD· 1 shared Goutham NarlaiD· 1 shared Indiraa DoraiveliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amber L. MosleyORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 14, 2025

PP2A activation drives aberrant macropinocytosis and cell death in pancreatic ductal adenocarcinoma

Garima Baral, Claire M. Pfeffer, Sara N. Filippelli…·Brittany L. Allen-Petersen

This study shows that PP2A activation inhibits macropinocytosis and induces cell death in pancreatic ductal adenocarcinoma, suggesting PP2A activators could be used with metabolic inhibitors as a new therapeutic strategy.

DOI 10.1101/2025.07.14.664742

humanexperimental assay