Author

Roberta Florea

ETH ZurichORCID 0009-0002-2716-1560Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexander LeitneriD· 2 shared Paola PicottiiD· 2 shared Alexander S. HauseriD· 1 shared Alvar D. GossertiD· 1 shared Anand VaithiaiD· 1 shared Angela Kosturanova· 1 shared Basavraj KhanppnavariD· 1 shared Bettina Brokowski· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Alexander LeitnerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 11, 2026

Neuronal calcium sensors emerge as novel adenylyl cyclase 8 regulators

Basavraj Khanppnavar, Roberta Florea, Dina Schuster…·Volodymyr M. Korkhov

This study identifies HPCAL1 as a Ca2+-dependent regulator of AC8, revealing a new mechanism for cAMP signaling regulation.

DOI 10.64898/2026.04.19.719435

humanproteomics

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Systems BiologyMolecular Systems BiologyPeer-reviewedJan 12, 2026

Limited proteolysis-coupled mass spectrometry captures proteome-wide protein structural alterations and biomolecular condensation in living cells

Franziska Elsässer, Roberta Florea, Felix Räsch…·Paola Picotti

The paper introduces in-cell LiP-MS to study protein structural changes and biomolecular condensates in live human cells, revealing structural alterations under stress and validating them with microscopy.

7 citationstop 1%

humanproteomics

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NeuroscienceScience AdvancesPeer-reviewedMar 14, 2025

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

Samuel George Usher, Estelle Toulmé, Roberta Florea…·Stephan Alexander Pless

The paper shows that SNARE complex proteins inhibit NALCN channel activity and that reducing NALCN currents promotes cell survival in syntaxin-depleted cells.

3 citations

experimental assay

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