Author

David M. Lopez

Stanford MedicineORCID 0009-0002-3116-0253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Cadence Seymour· 1 shared Christopher K. GlassiD· 1 shared Christopher W. BenneriD· 1 shared Debanjan DhariD· 1 shared Enikö SajtiiD· 1 shared Fenghua ZengiD· 1 shared Jason L. GuoiD· 1 shared John Lalith Charles RichardiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Cadence Seymour

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1 paper

Recent·Most cited

Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-inducedlung injury

Yohei Abe, Nathanael J. Spann, Wenxi Tang, Fenghua Zeng, Cadence Seymour, Sean Jansky, Jason L. Guo, Robert M. Huff, Kelly Chanthavixay, John Lalith Charles Richard, Miguel Mooney, Debanjan Dhar, Souradipta Ganguly, David M. Lopez, Michael Thornton Longaker, , Enikö Sajti

The paper identifies TREM2-p53 signaling as a determinant of oxygen-induced lung injury in mice, showing that TREM2 loss reduces inflammation and improves lung development.

Nature Immunology · Jul 25, 2025Peer-reviewedImmunology