Author

Sobita Kunwar

Utah State UniversityORCID 0009-0002-3248-8680Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Chase L. BeiseliD· 2 shared Ryan N. JacksoniD· 2 shared Aaron J. ThomasiD· 1 shared Amanda Martin· 1 shared Anne-Sophie Gribling-BurreriD· 1 shared Balwina KoopaliD· 1 shared Bingbing Yu· 1 shared Bronson Naegle· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Chase L. BeiselORCID

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2 papers

Recent·Most cited

Aminoacylated tRNA tails trigger auxiliary bacterial immunity

Yan Yan, Balwina Koopal, Sobita Kunwar, Oleg Dmytrenko, Eric Jenkins, Maximilian Feussner, Anne-Sophie Gribling-Burrer, Victor Sadilek, Natalie Yoho, Amanda Martin, Bingbing Yu, Florian Praetorius, Redmond P. Smyth, Ryan N. Jackson, Jack P. K. Bravo, Chase L. Beisel

The paper shows that cleaved aminoacylated tRNA tails trigger auxiliary bacterial immunity by activating Adt1, leading to mRNA cleavage and cellular dormancy.

bioRxiv · Oct 16, 2026 · PreprintMicrobiology

Target RNA-triggered CRISPR-Cas12a2 Preferentially Cleaves Collateral DNA over RNA

Sobita Kunwar, Thomson Hallmark, Sudeshna Manna, Dylan Keiser, Bronson Naegle, Aaron J. Thomas, Chase L. Beisel, Ryan N. Jackson

This study shows that Cas12a2 preferentially cleaves collateral DNA over RNA, revealing the mechanism and implications for CRISPR-based immunity and technology.

Nucleic Acids Research · May 28, 2026Peer-reviewedBiochemistry