Author
Utah State UniversityORCID 0000-0001-7403-3794Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yan Yan, Balwina Koopal, Sobita Kunwar…·Chase L. Beisel
The paper shows that cleaved aminoacylated tRNA tails trigger auxiliary bacterial immunity by activating Adt1, leading to mRNA cleavage and cellular dormancy.
Jingkun Zeng, Zhiyuan Cheng, Huadong Chen…·Jennifer A. Doudna
This paper develops a method to selectively kill cancer cells with TP53 mutations by using RNA-guided Cas12a2 to induce chromatin shredding through targeting cancer-specific transcripts.
Sobita Kunwar, Thomson Hallmark, Sudeshna Manna…·Ryan N. Jackson
This study shows that Cas12a2 preferentially cleaves collateral DNA over RNA, revealing the mechanism and implications for CRISPR-based immunity and technology.