Maximilian Feussner

The paper shows that cleaved aminoacylated tRNA tails trigger auxiliary bacterial immunity by activating Adt1, leading to mRNA cleavage and cellular dormancy.

This paper describes how the Druantia type III-A defense system in E. coli clears phage infections by recognizing single-stranded DNA and unwinding DNA duplexes directionally.

The paper identifies structured RNA motifs and Aca proteins that regulate anti-CRISPR gene expression in bacteriophages, revealing new regulatory mechanisms beyond DNA-binding HTH regulators.

This paper identifies viral single-guide RNAs (vsgRNAs) that subvert bacterial CRISPR-Cas9 immunity by sequestering Cas9 and redirecting its activity, and shows they can enable genome editing in mammalian cells.