Multi-omics and spatial analysis of microgravity-grown glioblastoma organoids reveals superior modeling of advanced disease after long-term spaceflight
Alice A. Burchett, Maksym Zarodniuk, Shelby Giza…·Meenal Datta
This study shows that microgravity-grown GBM organoids exhibit enhanced transcriptomic, proteomic, and architectural features associated with worse patient outcomes compared to ground controls.