Author

Someshwar Nath Jha

National Institute of ImmunologyORCID 0009-0002-3690-1399Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Nimesh GuptaiD· 2 shared Amit Kumar PandeyiD· 1 shared Ashish Kumar GuptaiD· 1 shared Bhishma Narayan Panda· 1 shared Bhushan Nikam· 1 shared Debasis DashiD· 1 shared Deepak Jena· 1 shared Jaswinder Singh MarasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Nimesh GuptaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 3, 2026

A Glycolysis-Fatty Acid Metabolic Axis Shapes Human Tfh Cell Function

Someshwar Nath Jha, Bhushan Nikam, Deepak Jena…·Nimesh Gupta

This study shows that early glycolysis inhibition enhances Tfh cell differentiation but impairs their function, revealing a glycolysis-fatty acid metabolic axis that controls Tfh function.

DOI 10.64898/2026.04.01.715763

humanbulk RNA-seq

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ImmunologybioRxivPreprintOct 7, 2025

Methionine modulates the metabolic-epigenetic axis as immunotherapeutic in tuberculosis

Nidhi Raj Yadav, Ashish Kumar Gupta, Soumya Sahoo…·Ranjan Kumar Nanda

This study shows methionine supplementation enhances pro-inflammatory responses and mycobacterial clearance in tuberculosis by modulating host metabolism and epigenetic pathways.

DOI 10.1101/2025.10.07.680834

mousebulk RNA-seq

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