Fusion Oncoprotein EWSR1::FLI1 Invades Nucleosomes at Consensus ETS Motifs and GGAA Microsatellites
Ruo-Wen Chen, Runwei Zhou, E. John Tokarsky, Megann A. Boone, Andrea K. Byrum, Michael Guy Poirier, Emily R. Theisen
This study investigates how EWSR1::FLI1 binds to nucleosomes and DNA motifs, revealing its pioneer factor properties and preference for GGAA repeats.
bioRxiv · Sep 18, 2026 · PreprintBiochemistry