Author

Luigi L. Nardella

German Cancer Research CenterORCID 0009-0002-4148-0306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea SacchettiiD· 1 shared Coen Linn· 1 shared Fatma Aktuna· 1 shared Holger GarniD· 1 shared Jens PuschhofiD· 1 shared Kim PauckiD· 1 shared Lior LobeliD· 1 shared Mark R. SchmittiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Andrea SacchettiORCID

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1 paper

Recent·Most cited

Western-style diet-induced microbial shifts and inflammation reprogram c-Kit⁺ secretory cells into targets for tumor initiation

Sara Silva, Paola Procopio, Valeriya V. Zinina, Solveig Turss, Rafael R. Segura Muñoz, Seyram Segbefia, Sena Bae, Lior Lobel, Luigi L. Nardella, Andrea Sacchetti, Rosalie Joosten, Coen Linn, Susanna Plugge, Mathijs P. Verhagen, Fatma Aktuna, , Mark R. Schmitt

This study shows that a Western-style diet reprograms c-Kit⁺ secretory cells into tumor-initiating cells via microbial shifts and inflammation.

bioRxiv · Jul 19, 2026 · PreprintCell Biology