Cancer BiologybioRxivPreprint
Telomere Dysfunction in Human Astrocytes Drives Acrocentric Chromosome Instability and Nucleolar Reorganization
Ogechukwu Mbegbu, Yi-An Chen, Yue Hao…·Floris P Barthel
This study shows that telomere dysfunction in human astrocytes leads to acrocentric chromosome instability and nucleolar reorganization through a combination of cytogenetic, imaging, and chromatin-contact analyses.
DOI 10.64898/2026.05.19.726354