Elena Y. Demireva

This study identifies mitochondrial scaffolds that regulate PIWI protein trafficking and pachytene piRNA biogenesis in mice, revealing a central role for chromatoid body precursors in piRNA complex formation.

This study shows that AIRE deficiency causes epididymitis and male infertility through immune-mediated fibrosis, iron deposition, and metal imbalance leading to sperm DNA damage.

This study shows that PNLDC1 is essential for piRNA 3' end trimming, LINE1 silencing, and spermatogenesis in mice, with pachytene piRNA trimming being critical for germ cell development.

The paper demonstrates successful CRISPR genome editing in the Nile grass rat, a diurnal rodent, establishing methods for reproductive and genetic manipulation.

This study develops a mouse model of GNAO1 R209H mutation, showing hyperlocomotion that is alleviated by risperidone.