Kelly Hu

This paper develops a method to rapidly generate human 8-cell-like cells (ri8CLCs) using small molecules, enabling efficient modeling of early embryogenesis.

This study identifies species-specific oxygen sensing as a key factor in limb regeneration, showing that reducing oxygen sensing in amphibians enhances regenerative capacity while mammals require oxygen-sensitive pathways.

The paper develops a limb organoid model to study how signaling centers direct cell fate and spatial organization during limb development.