Author

Sara M. Demczyszyn

Abramson Cancer CenterORCID 0009-0002-4761-8644Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Boa KimiD· 1 shared Boyoung KimiD· 1 shared Caitlyn E. BowmaniD· 1 shared Cholsoon JangiD· 1 shared Marie Celeste SimoniD· 1 shared Michael NojiiD· 1 shared Nathan J. CoffeyiD· 1 shared Schuyler Bowers· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Boa KimORCID

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1 paper

Recent·Most cited

Cancer BiologyJCI InsightPeer-reviewedOct 30, 2025

HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell Renal Cell Carcinoma

Wencao Zhao, Sara M. Demczyszyn, Nathan J. Coffey…·Boa Kim

This study shows HIF2α prevents GLS1 clustering in mitochondria, protecting ccRCC cells from glutamine deprivation, and suggests targeting GLS1 clustering could enhance HIF2 therapy.

3 citations

humanproteomics

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