Shan Gao

The paper shows that higher TREM2 expression in gliomas correlates with poor prognosis, but TREM2 deficiency does not improve outcomes in pre-clinical models, as it impairs myeloid cell phagocytosis and MHCII-dependent CD4+ T cell responses.

This study shows that inhibiting Yap in AT2 stem cells enhances alveolar regeneration and reduces pulmonary fibrosis, while inhibiting Taz worsens fibrosis.