Shan Gao

Genome-wide association study highlights 44 loci for transient ischemic attack and shared genetic architecture with stroke

This study identifies 44 genetic loci associated with transient ischemic attack (TIA) and finds shared genetic architecture with stroke through large-scale genome-wide association analyses.

Genome-wide cross-trait analysis of vascular dementia and Alzheimer's disease highlights novel loci and lung-brain axis

This study identifies novel genetic loci for vascular dementia and its association with lung function, and finds shared genetic risk factors with Alzheimer's disease.

Bromodomain protein IBD1 bridges histone acetylation and H2A.Z deposition to fine-tune transcription and prevent hyperactivation in Tetrahymena thermophila

This study identifies IBD1 as a bridge between histone acetylation and H2A.Z deposition, showing its role in maintaining transcriptional homeostasis by preventing hyperactivation.

Microfiber-Templated Porogel Bioinks Enable Tubular Interfaces and Microvascularization Down to the Building Blocks for 3D Bioprinting

This paper introduces a new bioink called microfiber-templated porogel (FTP) bioink that enables the creation of vascularized 3D bioprinted structures with tunable porosity and in-situ endothelialization.

Comprehensive genome annotation of the model ciliate Tetrahymena thermophila by in-depth epigenetic and transcriptomic profiling

This study improves gene annotation in Tetrahymena thermophila by integrating transcriptomic and epigenetic data, adding new genes and UTRs while identifying antisense transcripts.

Extensive Expansion of the Speedy gene Family in Homininae and Functional Differentiation in Humans

The paper identifies extensive expansion of the Speedy gene family in Homininae and reports functional differentiation in humans, including distinct expression patterns and prognostic roles in cancer.

Distinct nucleosome distribution patterns in two structurally and functionally differentiated nuclei of a unicellular eukaryote

The paper compares nucleosome distribution patterns between two nuclei in Tetrahymena thermophila, finding distinct positioning in the active MAC and delocalized patterns in the silent MIC.