Élodie Montaudon

This paper shows that the SF3B1 inhibitor pladienolide B inhibits DNA damage repair and counteracts platinum resistance in NSCLC by inducing genomic instability and altering DNA repair gene splicing.

This study develops a Tumor-on-Chip platform for rapid drug testing in breast cancer, showing high concordance with patient-derived xenografts and potential for clinical use.

This study uses spatial transcriptomics to analyze tumor microenvironment remodeling dynamics in triple-negative breast cancer, identifying early stromal programs as potential therapeutic targets.

The paper identifies a shared persistence program in triple-negative breast cancer across treatments and patients, revealing key drivers and mechanisms of drug resistance.