Author

Zayna Diaz

Icahn School of Medicine at Mount SinaiORCID 0009-0002-5526-9077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Clifford ChaoiD· 2 shared Dan HassoniD· 2 shared Elvin WagenblastiD· 2 shared Grace S. FreediD· 2 shared Isabella G. MartineziD· 2 shared Ke WangiD· 2 shared Levan MekerishviliiD· 2 shared Miguel Quijada ÁlamoiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Clifford ChaoORCID

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2 papers

Recent·Most cited

A CRISPR-Based Humanized Model Reveals Cooperative Role of STAG2 Loss in Familial GATA2-Deficient MDS Progression

Grace S. Freed, Miguel Quijada Álamo, L Lee, Ke Wang, Nikita Poddar, Subrina Persaud, Saul Carcamo, Persephone Fiore, Emma K Kim, Isabella G. Martinez, Mimi Zhang, Shayan Saniei, Clifford Chao, Levan Mekerishvili, Zayna Diaz, , Elvin Wagenblast

This paper uses a CRISPR-based humanized model to show that STAG2 loss cooperates with GATA2 deficiency to drive MDS progression through increased HSC self-renewal and myeloid bias.

Blood Advances · Sep 24, 2026Peer-reviewedCancer Biology

Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia

Ke Wang, Shayan Saniei, Nikita Poddar, Isabella G. Martinez, Clifford Chao, Subrina Autar, Persephone Fiore, Saul Carcamo, Meghana Sreenath, Jack H. Peplinski, Rhonda E. Ries, Anna Huo-Chang Mei, Noshin Azra Rahman, Levan Mekerishvili, Miguel Quijada‐Álamo, , Eric Chi Wai So

This study shows that the developmental stage of hematopoietic stem cells influences leukemic transformation, lineage hierarchy, and therapy response in pediatric leukemia.

Cancer Discovery · Dec 6, 2025Peer-reviewedCancer Biology