Author

Miguel Quijada‐Álamo

Tisch Cancer InstituteORCID 0000-0002-4831-4565Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Dan HassoniD· 3 shared Elvin WagenblastiD· 3 shared Ke WangiD· 3 shared Mimi ZhangiD· 3 shared Persephone FioreiD· 3 shared Clifford ChaoiD· 2 shared Grace S. FreediD· 2 shared Isabella G. MartineziD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Dan HassonORCID

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3 papers

Recent·Most cited

Disrupted chromatin architecture blocks B lymphopoiesis in Down syndrome

Zhicong Liao, Mimi Zhang, Brian Y. Soong, Bohan Zhu, Linda L. Boshans, Ke Wang, Miguel Quijada‐Álamo, Ifeoma Osakwe, Zhe Wang, Persephone Fiore, Dan Hasson, Elvin Wagenblast, Sai Ma

The paper develops ChromE-seq to study 3D chromatin architecture in fetal hematopoiesis, finding that T21 disrupts B-lineage development by altering chromatin connectivity and regulatory circuits.

bioRxiv · Oct 11, 2026 · PreprintGenomics

A CRISPR-Based Humanized Model Reveals Cooperative Role of STAG2 Loss in Familial GATA2-Deficient MDS Progression

Grace S. Freed, Miguel Quijada Álamo, L Lee, Ke Wang, Nikita Poddar, Subrina Persaud, Saul Carcamo, Persephone Fiore, Emma K Kim, Isabella G. Martinez, Mimi Zhang, Shayan Saniei, Clifford Chao, Levan Mekerishvili, Zayna Diaz, , Elvin Wagenblast

This paper uses a CRISPR-based humanized model to show that STAG2 loss cooperates with GATA2 deficiency to drive MDS progression through increased HSC self-renewal and myeloid bias.

Blood Advances · Sep 24, 2026Peer-reviewedCancer Biology

Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia

Ke Wang, Shayan Saniei, Nikita Poddar, Isabella G. Martinez, Clifford Chao, Subrina Autar, Persephone Fiore, Saul Carcamo, Meghana Sreenath, Jack H. Peplinski, Rhonda E. Ries, Anna Huo-Chang Mei, Noshin Azra Rahman, Levan Mekerishvili, Miguel Quijada‐Álamo, , Eric Chi Wai So

This study shows that the developmental stage of hematopoietic stem cells influences leukemic transformation, lineage hierarchy, and therapy response in pediatric leukemia.

Cancer Discovery · Dec 6, 2025Peer-reviewedCancer Biology