Author

Johann Moritz Weck

Center for NanoScienceORCID 0009-0002-5785-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Amelie Heuer‐JungemanniD· 2 shared Cornelia MonzeliD· 2 shared Xiaoyue ShangiD· 2 shared Gajen Thaventhiran· 1 shared J. BasquiniD· 1 shared Merve‐Z. Kesici· 1 shared Nina BartelsiD· 1 shared Riya Nair· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Amelie Heuer‐JungemannORCID

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2 papers

Recent·Most cited

High yield purification of an Isoleucine zipper modified CD95 Ligand with either biotin or DNA-oligomer binding domain for efficient Cell Apoptosis Induction

Xiaoyue Shang, Nina Bartels, Johann Moritz Weck, Sabine Suppmann, J. Basquin, Gajen Thaventhiran, Amelie Heuer‐Jungemann, Cornelia Monzel

This paper describes the design and production of a stabilized CD95L variant with improved apoptosis induction efficiency and functionalization capabilities.

BMC Biotechnology · Jul 1, 2025Peer-reviewedCell Biology

Effects of DNA Origami-Based Nanoagent Design on Apoptosis Induction in a Large 3D Spheroid Model

Johann Moritz Weck, Riya Nair, Merve‐Z. Kesici, Xiaoyue Shang, Svetozar Gavrilović, Cornelia Monzel, Amelie Heuer‐Jungemann

This study evaluates DNA origami-based nanoagents' ability to induce apoptosis in 3D spheroids, finding that rigid FasL attachment strategies are more effective than flexible ones.

Small · Apr 25, 2025Peer-reviewedBioengineering