Cancer BiologybioRxivPreprint
Targeting AXL Overcomes Adaptive Resistance to KRAS Inhibition in KRAS-Driven Cancer
Fredrik I. Thege, Annaliese Kramer, Norbert Kreisz…·Anirban Maitra
This study identifies AXL as a driver of adaptive resistance to KRAS inhibition and shows that combining AXL and KRAS inhibition improves tumor control and immune response in lung and pancreatic cancer models.