Author

Weijia Zhang

Chinese University of Hong Kong, ShenzhenORCID 0009-0002-6420-5307Unclaimed ORCID profile · follow to get notified of new preprints

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Weijia Zhang4 papers · Shandong University

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Richard D. YeiD· 2 shared Yezhou LiuiD· 2 shared Aijun LiuiD· 1 shared Aijun Liu· 1 shared Clàudia Llinàs del Torrent Masachs· 1 shared Leonardo Pardo· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

Richard D. YeORCID

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2 papers

Recent·Most cited

BiochemistryCell ReportsPeer-reviewedJun 24, 2024

Structural insights into agonist binding and activation of succinate receptor 1

Aijun Liu, Yezhou Liu, Weijia Zhang, Richard D. Ye

This study presents cryo-EM structures of SUCNR1-Gi complexes bound to succinate and epoxysuccinate, revealing key residues and structural changes involved in agonist binding and activation.

18 citations

𝕏 PostBluesky

ImmunologybioRxivPreprintDec 27, 2023

Structural basis for constitutive activation and CXCL1 recognition of human herpesvirus 8-encoded G protein-coupled receptor KSHV-GPCR

Aijun Liu, Yezhou Liu, Clàudia Llinàs del Torrent Masachs…·Richard D. Ye

This study determines the cryo-EM structures of KSHV-GPCR in complex with Gi and CXCL1, revealing structural mechanisms of constitutive activation and ligand binding.

DOI 10.1101/2023.12.27.573477

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