AI-guided discovery of atypical protein assemblies
AmirAli Toghani, Benjamin A. Seager, Yu Sugihara, Lisa-Marie Roijen, Juan M. Azcue, Maián Garro, Maryam Sargolzaei, Ioanna Morianou, Adeline Harant, Sam Gallop, Jiorgos Kourelis, Dan MacLean, Mauricio P. Contreras, Sophien Kamoun, Daniel Lüdke
The paper introduces SNI, a framework to identify atypical protein assemblies, and applies it to NLRs, finding an undecameric assembly in NRC7 orthologs.
bioRxiv · May 4, 2026 · PreprintBioinformatics