Adeline Harant

This study shows how a plant pathogen effector blocks the stepwise assembly of a helper NLR resistosome by stabilizing an intermediate state.

The paper introduces SNI, a framework to identify atypical protein assemblies, and applies it to NLRs, finding an undecameric assembly in NRC7 orthologs.

The study shows that autoactive mutants of tomato NRC proteins still induce cell death in prf mutants and in lettuce, indicating a unidirectional dependency in the NRC immune network.

The paper identifies a root-specific NLR gene cluster in tomato that confers resistance to nematodes and evolved from an ancient NRC network.

The paper shows that NRC3 evolved to resist suppression by a nematode effector, revealing a new type of gene-for-gene interaction between pathogens and host immune receptors.

The paper identifies horizontal mini-chromosome transfers in clonal blast fungus lineages, showing genetic exchange between host-associated isolates.

The paper bioengineers a plant NLR receptor to recognize a conserved fungal effector, resulting in durable resistance against blast fungus isolates.

The paper identifies and analyzes hypervariable mini-chromosomes in Magnaporthe oryzae isolates from different grass hosts, showing their role in genomic rearrangements and potential adaptive evolution.