Author

Seth Staller

St. Jude Children's Research HospitalORCID 0009-0002-7123-1394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Steven Burden· 3 shared Virginia A. ValentineiD· 3 shared Alaguraj VeluchamyiD· 1 shared Bensheng JuiD· 1 shared Brett Brown· 1 shared Brian J. AbrahamiD· 1 shared Damilola OluwalanaiD· 1 shared Daniel SaviciD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Steven Burden

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 24, 2026

Glucocorticoid receptor activation reorganizes Wnt/LEF1 regulatory circuitry associated with therapeutic response in B-cell acute lymphoblastic leukemia

Robert J. Mobley, Damilola Oluwalana, Gabriele Baniulyte…·Daniel Savic

This study shows that GR activation reorganizes Wnt/LEF1 regulatory circuitry in B-ALL, influencing therapeutic response and resistance through chromatin state changes and gene regulation.

DOI 10.64898/2026.09.23.752002

humanChIP-seq

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BioinformaticsbioRxivPreprintMay 21, 2026

zFISHer: Automated 3D Registration, Detection, and Colocalization with Interactive Curation for Sequential Multiplexed FISH

Seth Staller, Virginia A. Valentine, Steven Burden

DOI 10.64898/2026.05.19.726314

imagingexperimental assay

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Molecular BiologyNucleic Acids ResearchPeer-reviewedFeb 24, 2026

3D-super-enhancers are condensate-associated cis-regulatory communities

Jie Lv, Kelsey A. Maher, Li Dong…·Brian J. Abraham

The paper introduces BOUQUET, an algorithm that identifies 3D-super-enhancers as protein-rich cis-regulatory communities associated with co-activator condensates in mammalian cells.

5 citationstop 2%

humanmouse

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