Alon Zemer

This study shows that time-restricted feeding improves glucose intolerance and circadian disruption caused by weight cycling in young obese mice, but not in mid-aged mice.

This study shows that mid-aged mice normalize dysglycemia faster than young mice when reversing obesity, but their hypothalamic microgliosis worsens after diet reversal.

This study shows CD4 T cells differentiate into cytotoxic T cells in senescent-rich environments, and reducing senescent cells halts this differentiation, impacting aging and disease.

This study examines the effects of weight cycling on immune remodeling in metabolic tissues and finds that metabolic dysfunctions are uncoupled from inflammation in obese mice.

The paper uses snRNA-seq to analyze human subcutaneous and visceral adipose tissue, identifying classical and specialized adipocyte subtypes and depot-specific patterns.