Author

Frank Vrieling

Wageningen University & ResearchORCID 0000-0002-8064-672XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hendrik J.P. van der ZandeiD· 2 shared Rinke StienstraiD· 2 shared Alberto M. PereiraiD· 1 shared Alon ZemeriD· 1 shared Andries KalsbeekiD· 1 shared Anhui Wang· 1 shared Anita E. GrootemaatiD· 1 shared Anouk van der Linden· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Hendrik J.P. van der ZandeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia

Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet, Anita E. Grootemaat, Kirill Vlaskov, Chaja Feige Jacobs, Yannick d’Hargues, Nicole N. van der Wel, Frank Vrieling, Bauke V. Schomakers, Michel van Weeghel, Kimberly M. Bonger, Mark-David Levin, Eric Eldering, Arnon Philip Kater, Helga Simon‐Molas

bioRxiv · Jun 10, 2026 · PreprintImmunology

Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity

Han Jiao, Jarne Jermei, Xian Liang, Hendrik J.P. van der Zande, Frank Vrieling, Valentina Sophia Rumanova, Milan Dorscheidt, Felipe Corrêa‐da‐Silva, Anhui Wang, Ewout Foppen, Alberto M. Pereira, Dirk Jan Stenvers, TieMin LIU, Kimberly Bonger, Rinke Stienstra, , Chun‐Xia Yi

This study examines how time-restricted feeding affects microglial immunometabolism in obese rats, finding that TRF during the active phase reduces fat mass and alters microglial transcriptome rhythmicity, but does not reverse HFD-induced metabolic inflexibility.

Cell Reports · Oct 1, 2025Peer-reviewedImmunology

Weight cycling-induced hypothalamic and metabolic tissue immune remodeling is uncoupled from metabolic dysfunctions

Hendrik J.P. van der Zande, Alon Zemer, Frank Vrieling, Lisa Smeehuijzen, Brecht J. Attema, Habib Muallem, Jenny Jansen, Anouk van der Linden, Sivan Prass, Danielle W.R. Wessels, Meirong Ren, Yulia Haim, Evert M. van Schothorst, Sander Kersten, Assaf Rudich, Rinke Stienstra

This study examines the effects of weight cycling on immune remodeling in metabolic tissues and finds that metabolic dysfunctions are uncoupled from inflammation in obese mice.

bioRxiv · Jun 27, 2025 · PreprintImmunology