Cancer BiologybioRxivPreprint
Site-specific immunogenicity and anti-PD1 response in mismatch repair deficient lung adenocarcinoma models
Etna Abad, Ivan Zadra, Anastasia Krasko…·Ana Janic
This study compares immunotherapy responses in subcutaneous and orthotopic dMMR LUAD models, finding that orthotopic models show better anti-PD1 response with increased immune infiltration and CD4+ memory T cells.
DOI 10.1101/2025.01.13.632715