Daniel T. Swarr

The paper shows that the ARID1A-containing BAF complex is essential for lung development, proximal-distal axis specification, and cell fate acquisition during respiratory development.

The paper investigates the role of Cux1 in postnatal epithelial development, finding that its loss causes transient developmental delays in multiple tissues without affecting organogenesis or regeneration.

This study shows PRDM3 and PRDM16 regulate chromatin accessibility to support NKX2-1-driven alveolar epithelial differentiation and function, with loss leading to respiratory failure and lineage infidelity.

This study identifies Nkx2-1-driven chromatin topology changes in alveolar epithelial progenitor cells that regulate lung regeneration and differentiation.

The paper uses transcriptomic data from amniotic fluid and fetal tissues to identify biomarkers of fetal maturity in rhesus macaques, showing that cell-free RNA can predict lung compliance and gestational age.

The paper identifies PI3K signaling's role in regulating SOX9+ lung progenitor cell fate through gene regulatory networks using RNA-Seq and ATAC-Seq data.

This study shows that blocking inflammation in preterm primates prevents lung injury, preserving alveolar structure and function similar to chronic lung disease in newborns.