Author

Evelyn Hennigan

Icahn School of Medicine at Mount SinaiORCID 0009-0002-8311-4750Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Donghoon LeeiD· 2 shared John F. FullardiD· 2 shared Panos RoussosiD· 2 shared Abigail UchiteleviD· 1 shared Alain NdayisabaiD· 1 shared Alice BuonfiglioliiD· 1 shared Aram HongiD· 1 shared Ashley HarlockiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Donghoon LeeORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedAug 11, 2026

Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer's Disease

Donghoon Lee, James M. Vicari, Christian Porras…·Panos Roussos

The paper profiles human myeloid cells across aging and Alzheimer's disease, identifies AD-associated changes, and links GPNMB to neuroprotection via TREM2.

22 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 9, 2025

Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model

Louise Alessandra Mesentier-Louro, Camille Goldman, Sebastian Gaese…·Joel Blanchard

This study develops a human brain tissue model (miBrain) to show that APOE4 astrocytes with cholesterol dysregulation promote α-synuclein pathology through endolysosomal dysfunction.

4 citations

humanscRNA-seq

𝕏 PostBluesky