Author

Louise Alessandra Mesentier-Louro

Icahn School of Medicine at Mount SinaiORCID 0000-0002-0937-9331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail UchiteleviD· 1 shared Alain NdayisabaiD· 1 shared Alice BuonfiglioliiD· 1 shared Ashley HarlockiD· 1 shared Braxton Riley SchuldtiD· 1 shared Camille GoldmaniD· 1 shared Dimitrios KyriakisiD· 1 shared Donghoon LeeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Abigail UchitelevORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model

Louise Alessandra Mesentier-Louro, Camille Goldman, Sebastian Gaese, Alice Buonfiglioli, Dimitrios Kyriakis, Ashley Harlock, Alain Ndayisaba, Emily R. Sartori, Abigail Uchitelev, John F. Fullard, Evelyn Hennigan, Donghoon Lee, Braxton Riley Schuldt, Rikki B. Rooklin, Jonathan Barra, , Joel Blanchard

This study develops a human brain tissue model (miBrain) to show that APOE4 astrocytes with cholesterol dysregulation promote α-synuclein pathology through endolysosomal dysfunction.

bioRxiv · Feb 9, 2025 · PreprintNeuroscience