NeurosciencebioRxivPreprint
Localized calcium accumulations prime synapses for phagocyte removal in cortical neuroinflammation
Mehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero…·Martin Kerschensteiner
The paper shows that calcium accumulations in dendritic spines precede their removal by phagocytes in cortical inflammation, and blocking phagocyte activation prevents synapse loss.