Author

Barbara L. Hempstead

Weill Cornell MedicineORCID 0009-0002-9957-564XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Anna R. MalikiD· 1 shared Ewa Żurawska-PłaksejiD· 1 shared Ewelina ZiemlińskaiD· 1 shared Francis S. LeeiD· 1 shared Jarosław CendrowskiiD· 1 shared Nicholas C. MoranoiD· 1 shared Pouneh KermaniiD· 1 shared Roshelle S. SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Anna R. MalikORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 5, 2026

Expression of the human immunomodulatory protein, human B7-1 (CD80), accelerates neuroinflammation, synaptic loss, microvascular instability and lethality in a murine model of Alzheimers Disease

Víctor Danelon, Sarah C. Garrett-Thomson, Nicholas C. Morano…·Barbara L. Hempstead

This study shows that expressing human B7-1 in mice accelerates AD-like symptoms by enhancing neuroinflammation and synaptic loss.

DOI 10.64898/2025.12.30.697078

mouseexperimental assay

NeurosciencebioRxivPreprintJan 30, 2025

A-beta-induced distress of astrocytes triggers Alzheimer disease pathology through non-canonical delta secretase activity

Vanessa Schmidt, Ewelina Ziemlińska, Tomasz Obrębski…·Anna R. Malik

This study shows that impaired astrocyte stress response to amyloid-beta activates delta secretase, leading to amyloid and tau pathologies in Alzheimer's disease.

1 citation

mouseexperimental assay