NeurosciencebioRxivPreprint
A-beta-induced distress of astrocytes triggers Alzheimer disease pathology through non-canonical delta secretase activity
Vanessa Schmidt, Ewelina Ziemlińska, Tomasz Obrębski…·Anna R. Malik
This study shows that impaired astrocyte stress response to amyloid-beta activates delta secretase, leading to amyloid and tau pathologies in Alzheimer's disease.
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