Author

Prathith Bhargav

Indian Institute of Science Education and Research PuneORCID 0009-0003-0380-9438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Arnab MukherjeeiD· 2 shared Amrita Brajagopal HazraiD· 1 shared Ateek ShahiD· 1 shared Janhavi Borkar· 1 shared Lavisha ParabiD· 1 shared Nishad MatangeiD· 1 shared Pratishruti Panda· 1 shared Reman Kumar SinghiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Arnab MukherjeeORCID

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2 papers

Recent·Most cited

MicrobiologyACS Synthetic BiologyPeer-reviewedOct 28, 2026

The biosynthesis of FAD nucleotide analogues in Escherichia coli alters its sensitivity to aminoglycoside antibiotics

Ateek Shah, Shreya Mahato, Prathith Bhargav…·Amrita Brajagopal Hazra

This study shows that engineering FAD biosynthesis in E. coli to produce nucleotide analogues increases tolerance to aminoglycoside antibiotics by altering metabolic pathways.

DOI 10.1021/acssynbio.6c00495

E. colimetabolomics

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BioinformaticsJournal of Chemical Theory and ComputationPeer-reviewedDec 20, 2024

AlphaMut: a deep reinforcement learning model to suggest helix-disrupting mutations

Prathith Bhargav, Arnab Mukherjee

AlphaMut uses reinforcement learning to predict helix-disrupting mutations by analyzing amino acid effects on protein structure.

2 citations

protein structuredeep learning

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