Millie J. Thackray

This study identifies TRPML1 loss as a cause of lysosomal calcium failure and astrocyte dysfunction in Alzheimer's Disease, showing that restoring TRPML1 can prevent disease progression.

This study identifies glycogen metabolism as a key regulator of microglial function in Alzheimer's disease, showing that glycogenolysis drives microglial activation and that inhibiting it reduces Abeta uptake and functional impairment.