Disha Shah

This study identifies TRPML1 loss as a cause of lysosomal calcium failure and astrocyte dysfunction in Alzheimer's Disease, showing that restoring TRPML1 can prevent disease progression.

The paper shows that astrocyte calcium dysfunction leads to early network hyperactivity in Alzheimer's Disease, which can be reversed by restoring calcium signaling.

This study identifies reproducible resting-state networks in the mouse brain across multiple centers using standardized rsfMRI analysis.

This study shows that CYFIP1 haploinsufficiency in mice causes reduced brain functional connectivity and white matter defects, linking it to neuropsychiatric disorders like Autism and Schizophrenia.

This study shows that bottom-up sensory processing in rats reduces activity and functional connectivity in the default mode like network, similar to top-down attention effects in humans.