H.L Eng

The paper identifies two intramolecular interfaces that regulate WDR44 conformation and Rab11 binding, showing how pathogenic mutations disrupt this regulation.

This study defines DNAJA2 co-chaperone client selectivity using pulse-SILAC and BioID to reveal distinct protein pools associated with DNAJA2 based on structural and physicochemical properties.

This study identifies Hoi1 as an adaptor that targets BLTP2-like proteins to ER-PM contact sites in yeast, regulating lipid homeostasis and showing conservation in worms and flies.

The paper identifies cytosolic mutant proteins degraded by the proteasome and shows DNAJA2 stabilizes some mutants while being dispensable for wild-type proteins.