Author

Joseph Brake

University of MichiganORCID 0009-0009-5924-2585Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron Paul LandryiD· 1 shared David A. HannaiD· 1 shared Eranthie WeerapanaiD· 1 shared Qianni PengiD· 1 shared Rashi SinghaliD· 1 shared Roshan KumariD· 1 shared Ruma V. BanerjeeiD· 1 shared Yatrik Madhukar ShahiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Aaron Paul LandryORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintJul 24, 2025

Hydrogen sulfide increases intracellular oxygen and regulates the HIF response

Joseph Brake, David A. Hanna, Roshan Kumar…·Ruma V. Banerjee

This study shows hydrogen sulfide increases intracellular oxygen and destabilizes HIF-1, altering hypoxia sensing and potentially contributing to O2 toxicity diseases.

1 citation

mousemetabolomics

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