Ekaterina Khalizeva

The paper shows that mammalian cells produce extended HP1β isoforms that alter effector binding preferences, affecting heterochromatin organization.

This study shows that 5' UTR length influences alternative N-terminal protein isoform production through start codon selection and demonstrates this in health and disease.

The paper identifies and validates new TDMD-triggering sites in mouse models, showing their role in microRNA degradation and growth regulation through imprinted gene networks.

This study identifies SRSF12 as a primate-specific splicing factor that induces tissue-specific gene expression programs in human cells.

The paper shows that during prolonged mitotic arrest, the transcriptome is stabilized through increased mRNA half-lives and reduced deadenylation, dependent on PABPC1 and PABPC4.

The paper identifies differentially-localized protein isoforms generated by alternative start codon selection and shows their role in mitochondrial function, evolution, and disease.