Yuen Ngan Fan

This study identifies a novel anticonvulsant compound that targets neuronal homeostasis by increasing Pumilio expression, showing efficacy in Drosophila and mouse seizure models.

The paper validates four Drosophila premotor interneuron driver lines using electrophysiology, confirming their monosynaptic connection to the aCC motoneuron.

The paper shows that manipulating activity of a specific excitatory interneuron during a critical period in Drosophila larval development alters network tuning, with nitric oxide signaling playing a role dependent on prior network activity.