ImmunologybioRxivPreprint
Mode of T cell priming durably shapes the TCR repertoire, effector function and α4β1 integrin expression of human virus-specific CD4+ T cells
Elie Antoun, Guihai Liu, Deshni Jayathilaka…·Tao Dong
This study compares how natural infection versus vaccination primes human CD4+ T cells, showing differences in TCR diversity, effector function, and integrin expression years later.