Author

Caner Akıl

University of OxfordORCID 0000-0002-9464-1903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Peijun ZhangiD· 3 shared Yanan ZhuiD· 2 shared Alexander J. MentzeriD· 1 shared Danning Dong· 1 shared Elie AntouniD· 1 shared Eric O. FreediD· 1 shared Esra BalıkçıiD· 1 shared Guihai LiuiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Peijun ZhangORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 23, 2025

Uncovering structural determinants of peptide recognition by public and private T-cell receptors

Caner Akıl, Yanchun Peng, Julia McCarthy…·Peijun Zhang

The paper identifies structural differences in TCR recognition of the same pMHC ligand using cryo-EM, showing how similar β chains can pair with different α chains to produce distinct recognition modes.

DOI 10.1101/2025.11.23.690020

humanproteomics

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MicrobiologyNature CommunicationsPeer-reviewedJun 3, 2025

Unveiling the Complete Spectrum of SARS-CoV-2 Fusion Stages by In Situ Cryo-ET

Caner Akıl, Jialu Xu, Juan Shen, Peijun Zhang

This study uses cryo-ET to capture complete SARS-CoV-2 fusion intermediates, revealing structural changes and the inhibitory effect of the WS6 S2 antibody.

24 citationstop 1%

experimental assay

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MicrobiologyScience AdvancesPeer-reviewedMay 9, 2025

Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity

Long Chen, Yuta Hikichi, Juan S. Rey…·Peijun Zhang

This study shows that an ordered mature MA lattice is not required for HIV-1 infectivity, as a triple mutant lacking this structure remains infectious.

6 citations

humanexperimental assay

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