ImmunologyJournal of Medicinal ChemistryPeer-reviewed
Small Molecule Modulation of MHC-I Surface Expression: A Click Chemistry-Based Discovery Approach
Sarah E. Newkirk, Joey J. Kelly, Mahendra D. Chordia…·Marcos M. Pires
The paper identifies Hsp90 inhibitors as MHC-I inducers and develops novel compounds using click chemistry to enhance T cell activation and reduce toxicity.