Author

Saana Vihuri

University of HelsinkiORCID 0009-0003-6969-8443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Angela ChouiD· 1 shared Asma Lasram· 1 shared Christoph PollmanniD· 1 shared Giray EnkaviiD· 1 shared Ilpo VattulaineniD· 1 shared Jacob PiehleriD· 1 shared James Jeiwen ChouiD· 1 shared Min CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Angela ChouORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedApr 28, 2026

Structural Rewiring of IL-7R Dimerization by an Oncogenic Transmembrane Mutation Can Be Reversed by Rational Design

Qian Wang, Min Chen, Asma Lasram…·James Jeiwen Chou

This study identifies an oncogenic TMD mutation in IL-7R that causes ligand-independent signaling and shows that rationally designed transmembrane helices can reverse this effect.

1 citation

humanproteomics

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