Giray Enkavi

This study shows that TNS1 phase separation regulates adhesion dynamics by controlling the availability of inactive adhesion proteins through phosphorylation-dependent condensate formation.

This study identifies an oncogenic TMD mutation in IL-7R that causes ligand-independent signaling and shows that rationally designed transmembrane helices can reverse this effect.

The paper identifies CRAC and CARC motifs in RTK transmembrane domains, showing cholesterol interaction with TRKB's CARC motif and its effect on BDNF binding.

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.