Author

Heidi A. F. Dewling

Centre québécois sur les matériaux fonctionnelsORCID 0009-0003-7082-948XUnclaimed ORCID profile · follow to get notified of new preprints

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Biophysics· 1

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Approach:experimental assay· 1

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Calvin J. GordoniD· 1 shared Cynthia X. Li· 1 shared Dana KocíncováiD· 1 shared Egor P. TchesnokoviD· 1 shared Gonzalo CosaiD· 1 shared Hery W. LeeiD· 1 shared Matthias GötteiD· 1 shared Maulik D. BadmaliaiD· 1 shared

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Calvin J. GordonORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintJan 10, 2025

Single-molecule assay reveals the impact of composition, RNA duplex, and inhibitors on the binding dynamics of SARS-CoV-2 polymerase complex

Terri C. Lovell, Heidi A. F. Dewling, Cynthia X. Li…·Gonzalo Cosa

This study uses a single-molecule assay to analyze the binding dynamics of SARS-CoV-2 polymerase complex subunits with RNA, revealing differences in binding stability between co-expressed and reconstituted complexes and the effects of inhibitors.

DOI 10.1101/2025.01.10.632212

experimental assay

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