Author

Angel Caitlin Bondoy

Indiana University BloomingtonORCID 0009-0003-7133-6943Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Edward James SarrainiD· 1 shared Feng GuoiD· 1 shared Hengyao NiuiD· 1 shared Qi CaoiD· 1 shared Quan WangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Edward James SarrainORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistrybioRxivPreprintApr 21, 2026

PARP1 regulates the genomic ribonucleotide processing activity of TOP1 to prevent the formation of toxic TOP1-DNA adducts and the associated mutations.

Edward James Sarrain, Quan Wang, Angel Caitlin Bondoy…·Hengyao Niu

This study shows PARP1 prevents TOP1 from causing deletions at STRs by inhibiting TOP1-DNA adduct formation, which could inform therapies for cancers with RNase H2 mutations.

DOI 10.64898/2026.04.16.719024

humanexperimental assay

𝕏 PostBluesky